List of All Drops With Sodium Hyaluronate Help with Dry Eye Symptoms and Conjunctivochalasis symptoms: Here is a list

Some studies have shown that drops with a prospective unmasked study showed that an artificial tear containing isotonic glycerol and sodium hyaluronate can in fact reduce the severity of Conjunctivochalasis.43 

**All of below excetpt Paralube



Reference:
1.
https://dryeyeshop.com/pages/lubricant-ingredients-reference-list

2. Clin Ophthalmol. 2017; 11: 631–638.

Published online 2017 Apr 6. doi:  10.2147/OPTH.S131384

PMCID: PMC5388258

PMID: 28435213

Comparison of 0.2% and 0.18% hyaluronate eye drops in patients with moderate to severe dry eye with keratitis or keratoconjunctivitis

Dorothea Groß,1 Marc Childs,2 and Jean-Marie Piaton3

Author information ► Copyright and License information ► Disclaimer

This article has been cited by other articles in PMC.

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Abstract

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Purpose

Comparison of efficacy and safety of 0.2% and 0.18% hyaluronic acid (HA) eye drops three times a day (tid) in patients with moderate to severe dry eye disease, related to keratitis or keratoconjunctivitis.

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Patients and methods

Prospective, multicenter, randomized, single-masked, phase IIIb, noninferiority study (0.2% HA vs 0.18% HA) in two parallel groups over a period of 84 days. N=70 patients were evaluated. Primary efficacy outcome was ocular surface (OS) staining change on day 35 (D35), compared to baseline. Fluorescein and lissamine green were used for staining of cornea and conjunctiva. Secondary efficacy outcome included tear film breakup time, OS staining score on day 84 (D84), ocular comfort index, as well as patients’ and doctors’ evaluation.

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Results

Compared to day 0 (D0), 0.2% HA achieved a 47.7% reduction in staining score (−3.00±2.81 [standard deviation] points, n=38 patients) at D35; 0.18% HA showed a 41.2% reduction (−2.59±2.20 [standard deviation] points, n=32 patients). Statistical analysis showed noninferiority in efficacy of 0.2% HA compared to 0.18% HA on D35. At D84, the reduction in staining score had further increased to 64.5% for 0.2% HA and to 56.4% for 0.18% HA. Both eye drops improved tear film breakup time and ocular comfort index values. Investigators and patients assessed both treatments with 5 of 7 points (Likert Scale, medians). The rate of adverse events (AE) was 2.3% for 0.2% HA and 7.1% for 0.18% HA with no serious AE.

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Conclusion

Product	Packaging	Active ingredients	Inactive ingredients (preservative highlighted)
Refresh Classic (Allergan)	30 PF vials (0.4 mL)	Polyvinyl Alcohol 1.4% Povidone 0.6%	Purified water, sodium chloride. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Refresh Tears (Allergan)	15mL bottle	Carboxymethylcellulose Sodium	Oxychloro complex, Sodium Borate decahydrate, Sodium chloride, Potassium chloride, Calcium chloride dihydrate, Magnesium chloride hexahydrate, Boric acid, Sodium hydroxide to adjust pH and Purified water.
Refresh Plus (Allergan)	30 PF vials (0.4 mL)	Carboxymethylcellulose sodium 0.5%	Calcium chloride; magnesium chloride; potassium chloride; purified water; sodium chloride; and sodium lactate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Refresh Optive (Allergan)	30 PF vials (0.4 mL)	Carboxymethylcellulose sodium 0.5%, Glycerin0.9%	Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate; and sodium citrate dihydrate.
	15mL bottle		Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; PURITE® (stabilized oxychloro complex); sodium borate decahydrate; and sodium citrate dihydrate.
Refresh Optive Advanced (Allergan)	30 PF vials (0.4 mL)	Carboxymethylcellulose sodium 0.5% Glycerin1% Polysorbate 80 0.5%	Boric acid; carbomer copolymer type A; castor oil; erythritol; levocarnitine; purified water; and sodium hydroxide.
	10mL bottle		Boric acid; castor oil; erythritol; levocarnitine; carbomer copolymer type A; purified water; and PURITE®(stabilized oxychloro complex). May also contain sodium hydroxide to adjust pH.
Refresh Optive MEGA-3 (Allergan)	30 PF vials (0.4 mL)	Carboxymethylcellulose sodium 0.5% Glycerin1% Polysorbate 80 0.5%	Boric acid; butylated hydroxyl toluene; castor oil; erythritol; flaxseed oil; levocarnitine; pemulen TR-2; polyoxyl 40 stearate; purified water; sodium hydroxide; trehalose.
Refresh Celluvisc (Allergan)	30 PF vials (0.4 mL)	Carboxymethylcellulose sodium 1%	Calcium chloride, potassium chloride, purified water, sodium chloride, and sodium lactate.
Refresh Optive Gel Drops (Allergan)	10mL bottle	Carboxymethylcellulose sodium 10mg in 1mL, glycerin 9mg in 1mL	Boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; PURITE® (stabilized oxychloro complex); sodium borate decahydrate; sodium citrate dihydrate; purified water.
Refresh PM ointment (Allergan)	3.5g tube	Mineral Oil 42.5%White Petrolatum 57.3%	Lanolin alcohols
Refresh LacriLube (Allergan)	3.5g tube	Mineral Oil 42.5%White Petrolatum 56.8%	Chlorobutanol and lanolin alcohols.
Refresh Liquigel (Allergan)	15mL bottle	Carboxymethylcellulose sodium 1%	Boric acid, calcium chloride, magnesium chloride, potassium chloride, purified water, PURITE® (stabilized oxychloro complex), sodium borate, and sodium chloride.
Systane Ultra (Alcon)	25 PF vials (0.7 mL) 60 PF vials (0.7 mL)	Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%	Aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
	10mL bottle		Aminomethylpropanol, boric acid, hydroxypropyl guar, POLYQUAD* (polyquaternium-1) 0.001% preservative, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Balance (Alcon)	10mL bottle	Propylene Glycol 0.6%	Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxyl 40 stearate, POLYQUAD® (polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Complete (Alcon)	10mL bottle (1/3 fl oz)	Propylene Glycol 0.6%	Boric acid, dimyristoyl phosphatidylglycerol, edetate disodium, hydroxypropyl guar, mineral oil, polyoxl 40 Stearate, POLYQUAD(polyquaternium-1) 0.001% preservative, sorbitan tristearate, sorbital and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane (Alcon)	28 PF vials (0.4 mL)	Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%	Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
	15mL bottle		Boric acid, calcium chloride, hydroxypropyl guar, magnesium chloride, polyquaternium-1 as a preservative, potassium chloride, purified water, sodium chloride, zinc chloride. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Nighttime ointment (Alcon)	3.5g tube	White petrolatum 94% Mineral oil 3%	Anhydrous Liquid Lanolin 3%.
Systane Lubricant Eye Gel (Alcon)	10g	Hypromellose (0.3%)	Carbopol 980, phosphonic acid, purified water, sodium perborate and sorbitol. May contain sodium hydroxide to adjust pH.
Systane Gel Drops (Alcon)	10mL bottle	Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%	Aminomethylpropanol, boric acid, edetate disodium, hydroxypropyl guar, POLYQUAD® (polyquaternium-1)0.001% preservative, potassium chloride, sodium chloride, sorbitol and purified water. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Day & Night (Alcon)	Two 10mL bottles (Systane Gel Drops and Systane Ultra)	See Systane Gel Drops and Systane Ultra	See Systane Gel Drops and Systane Ultra
Systane Sport (Alcon)	Two 10mL bottles	Polyethylene Glycol 400 0.4% Lubricant Propylene Glycol 0.3%	Aminomethylpropanol, boric acid, hydroxypropyl guar, POLYQUAD® (polyquaternium-1) 0.001% preservative, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Systane Contacts (Alcon)	12mL bottle	dextran, hydroxypropyl methylcellulose	sodium chloride, potassium chloride, with edetate disodium 0.1% and POLYQUAD® (polyquaternium-1)
Genteal Mild (Alcon)	15mL / 25mL bottle	Hypromellose 0.2%	Boric acid, calcium chloride dihydrate, GenAqua (sodium perborate), phosphonic acid, potassium chloride, purified water, and sodium chloride
Genteal Moderate (Alcon)	15mL bottle	Dextran 70 0.1%, Glycerin0.2%, Hypromellose 0.3%	Boric acid, calcium chloride, glycine, hydrochloric acid and/or sodium hydroxide (to adjust pH), magnesium chloride, POLYQUAD® (polyquaternium-1) 0.001% preservative, polysorbate 80, potassium chloride, purified water, sodium chloride, zinc chloride.
Genteal Gel (Severe) (Alcon)	10g tube	Hypromellose 0.3%.	carbopol 980, phosphoric acid, purifed water, sodium hydroxide, sodium perborate, and sorbitol
Genteal ointment (Alcon)	3.5g	White petrolatum 93% Mineral oil 4%	anhydrous liquid lanolin
Genteal Tears (Alcon) Previously Tears Naturale Free	36 PF Vials (0.9 mL)	Dextran 70 0.1%, Hypromellose 2910 0.3%	Potassium Chloride, Purified Water, Sodium Borate, Sodium Chloride, May contain: Hydrochloric Acid, Sodium Hydroxide
Bion Tears (Alcon)	28 PF vials (0.4 mL)	Dextran 70 0.1%, Hypromellose 2910 0.3%  NOTE: Are you looking for Tears Naturale (discontinued). Bion Tears has the same active ingredients but some slight differences in the inactives.	Calcium chloride, magnesium chloride, potassium chloride, purified water, sodium bicarbonate, sodium chloride, zinc chloride, hydrochloric acid and/or sodium hydroxide and/or carbon dioxide to adjust pH.
Soothe XP (Bausch & Lomb)	15mL bottle	Light mineral oil (1.0%), Mineral oil (4.5%)	boric acid, edetate disodium, octoxynol-40, polyquaternium-1 (preservative), polysorbate 80, purified water, sodium borate decahydrate. May contain hydrochloric acid and/or sodium hydroxide (to adjust pH).
Soothe Long Lasting Hydration (Bausch & Lomb)	15mL bottle	Povidone (2.0%)	benzalkonium chloride (0.005%), boric acid, edetate disodiumdihydrate, purified water, sodium borate, sodium chloride, tyloxapol. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH.
Soothe Hydration (Bausch & Lomb)	15mL bottle	Povidone (1.25%)	boric acid, potassium chloride, sodium borate and sodium chloride;preserved with edetate disodium 0.1% and sorbic acid 0.1%
Soothe Preservative Free Lubricant (Bausch & Lomb)	28 PF Vials (0.6 mL)	Glycerin (0.6%) Propylene Glycol (0.6%)	boric acid, hydroxyalkylphosphonate, purified water, sodium alginate, sodium borate
Soothe Night Time Ointment (Bausch & Lomb)	3.5g tube	Mineral oil (20%), White petrolatum (80%)	None. Note - this is one of the only lubricant ointments on the list WITHOUT lanolin alcohol (6/14/18)
Advanced eye relief dry eye rejuvenation (Bausch & Lomb)	15mL bottle	Glycerin (0.3%) Propylene glycol (1.0%)	benzalkonium chloride (0.01%), boric acid, edetate disodium, potassium chloride, purified water, sodium borate, sodium chloride. Hydrochloric acid and/or sodium hydroxide may be used to adjust pH
Oasis Tears (Oasis Medical)	30 PF vials (0.3 mL)	Glycerin (0.2%)	Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.
Oasis Tears Plus (Oasis Medical)	30 PF vials (0.3 mL)	Glycerin (0.2%)	Hyaluronan, sodium chloride, sodium phosphate dibasic, sodium phosphate monobasic, water.
FreshKote (Focus Laboratories)	15mL bottle	Polyvinyl pyrrolidone2.0%, Polyvinyl alcohol 2.7%	Boric acid, Disodium edetate dihydrate, Ethanol, Glycerin, Lecithin, Polixetonium, Polysorbate-80, Potassium chloride, Purified water, Sodium chloride
Retaine MGD (Ocusoft) (Equivalent to Cationorm which is sold in Europe)	30 PF vials (0.4 mL)	Light Mineral Oil (0.5) Mineral Oil (0.5%)	Cetalkonium chloride, glycerol, poloxamer 188, tris hydrochloride, tromethamine, tyloxapol, water for injection.
Retaine HPMC (Ocusoft)	10mL bottle (preservative free)	Hypromellose 0.3%	Citric acid, sodium citrate, sorbitol, water for injection.
Retaine CMC (Ocusoft)	30 PF vials (0.6 mL)	Carboxymethylcellulose sodium 0.5%	Calcium chloride, magnesium chloride, potassium chloride, purified water, sodium chloride, sodium lactate. May also contain hydrochloric acid and/or sodium hydroxide to adjust pH.
Retaine PM (Ocusoft)	5g tube	Mineral oil (20%) White petrolatum (80%)	none
TheraTears dry eye therapy (Akorn)	30mL bottle	Sodium Carboxymethyl Cellulose (0.25%)	Borate Buffers, Calcium Chloride, Dequest, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Perborate, Sodium Phosphate
	32 PF vials (0.6 mL)		Borate Buffers, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride and Sodium Phosphate.
TheraTears nighttime dry eye therapy (gel) (Akorn)	28 PF vials (0.6 mL)	Sodium Carboxymethyl Cellulose (1%)	Borate Buffer, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Water (Purified), Sodium Bicarbonate (Baking Soda), Sodium Chloride, Sodium Phosphate
Contact lens comfort drops (Akorn)	15mL bottle	Carmellose sodium	Borate Buffer, Sodium Chloride, Potassium Chloride, Sodium Bicarbonate (baking soda), Calcium Chloride, Magnesium Chloride, Sodium Phosphate, Sodium Perborate stabilized with phosphonic acid
NanoTears TF (Altaire)	15mL bottle 30mL bottle	Polyethylene Glycol 400 0.4% Propylene Glycol 0.3%	Boric acid, castor oil, gellan gum, glycerin, hydroxyethylcellulose, polyoxyl 35 castor oil,polysorbate 80, sorbitol, tromethamine, Vanish (stabilized peroxy complex as a preservative) and purified water.
NanoTears TF PF (Altaire)	32 0.6mL vials	Polyethylene Glycol 400 0.4% Propylene Glycol 0.3%	Boric acid, gellan gum, glycerin, hydroxyethylcellulose, polyoxyl 35 castor oil, polysorbate 80, sorbitol, tromethamine, and purified water.
NanoTears XP (Altaire)	10mL bottle	Polyethylene Glycol 400 0.4% Propylene Glycol 0.3%	Boric acid,  castor oil, gellan gum, glycerin, hydroxyethylcellulose, polyoxyl 35 castor oil, polysorbate 80, sorbitol, tromethamine, Vanish (stabilized peroxy complex as a preservative) and purified water. Sodium hydroxide or hydrochloric acid may be added to adjust the pH.
BlinkContactsLubricating Eye Drops	(10mL) bottle	Polyethylene Glycol 400 0.25%	Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure Brand) as a Preservative; Sodium Hyaluronate.
BlinkTears Lubricating Eye Drops	15 mL bottle	Polyethylene Glycol 400 0.25%	Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure Brand) as a Preservative; Sodium Hyaluronate.
Blink GelTears Lubricating Eye Drops	10 mL bottle	Polyethylene Glycol 400 0.25%	Boric Acid; Calcium Chloride; Magnesium Chloride;Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Chlorite (OcuPure brand) as a preservative; Sodium Hyaluronate.
BlinkTears Preservative Free Lubricating Eye Drops	0.4 mL PF Vials	Polyethylene Glycol 400 0.25%	Boric Acid; Calcium Chloride; Magnesium Chloride; Potassium Chloride; Purified Water; Sodium Borate; Sodium Chloride; Sodium Hyaluronate.
Puralube Ointment	3.5g tube	85% white petrolatum 15% light mineral oil	n/a Note: This is one of the very few ointments that do NOT contain lanolin alcohol.
Clear Eyes Pure Relief for Dry Eyes	"240 drops" PF multi-dose bottle	Glycerin 0.25%	Boric acid, purified water, sodium borate, sodium chloride, sodium hyaluronate
Clear Eyes Outdoor Dry Eye Protection	Bottle	Polyvinyl alcohol 0.5% Povidone 0.6%	Benzalkonium Chloride, Dextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)
Clear Eyes Natural Tears Lubricant	Bottle	Polyvinyl alcohol 0.5% Povidone 0.6%	Benzalkonium Chloride, Dextose, Edetate Disodium, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Sodium Citrate, Sodium Phosphate (mono- and dibasic)
Visine Dry Eye Relief	15mL bottle	Glycerin 0.2% Hypromellose 0.2% Polyethylene glycol 400 1%	ascorbic acid, benzalkomium chloride, boric acid, dextrose, disodium phosphate, glycine, magnesium chloride, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate
Visine Tired Eye Dry Eye Relief	15mL bottle	Glycerin 0.2% Hypromellose 0.36% Polyethylene glycol 400 1%	ascorbic acid, boric acid, dextrose, glycine, magnesium chloride, polyquaternium-42, potassium chloride, purified water, sodium borate, sodium chloride, sodium citrate, sodium lactate, sodium phosphate dibasic