What Conditions or Syndromes are associated with Cataracts?

What Conditions or Syndromes are associated with Cataracts?


This is a great list but would add:

Trauma of any kind and
GENETIC PREDISPOSITION of any kind

Wilson's syndrome: hepatolenticular degeneration: a neurological condition
Cohen syndrome,
Degos disease, 
Dubowitz syndrome


Sandra Lora Cremers, MD, FACS

Modified from: http://www.cybersight.org/bins/volume_page.asp?cid=1-2897-3640-3659

Lens -  SYNDROMES AND DISEASES ASSOCIATED WITH CATARACTS

Lecture 18 of 21  NEXT»

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1. Aberfeld syndrome (blepharophimosis associated with generalized myopathy) 2. Acrodermatitis chronic a atrophicans 3. Addison syndrome (adrenal cortical insufficiency) 4. Albinism 5. Albright hereditary osteodystrophy (pseudohypoparathyroidism) 6. Alopecia areata *7. Alport syndrome (hereditary nephritis) 8. Alström disease (cataract and retinitis pigmentosa) 9. Andogsky syndrome (atopic cataract syndrome) 10. Anterior segment ischemia syndrome 11. Apert syndrome (acrocephalosyndactylism syndrome) 12. Apical malformations associated with cataracts 13. Arteriovenous fistula 14. Arthrogryposis multiplex congenita 15. Aspergillosis *16. Atopic dermatitis syndrome 17. Autosomal dominant foveal hypoplasia and presenile cataract syndrome (O'Donnell-Pappas syndrome) 18. Bassen-Kornzweig syndrome (abetalipoproteinemia) 19. Bloch-Sulzberger syndrome (incontinentia pigmenti) 20. Bonnevie-Ullrich syndrome (pterygolymphangiectasia) 21. Bourneville syndrome (tuberous sclerosis) 22. Buerger disease (thromboangiitis obliterans) 23. Caisson syndrome (bends) 24. Capsular exfoliation syndrome 25. Carotid artery syndrome 26. Cataract and hypertrophic neuropathy-autosomal recessive 27. Cataract with microcornea and coloboma of iris-autosomal dominant 28. Cataract, floriform-autosomal dominant 29. Cataract and cardiomyopathy-autosomal recessive 30. Cataract, congenital, or juvenile-autosomal recessive 31. Cataract, congenital total, with posterior sutural opacities in heterozygotes-X-linked 32. Cataract, congenital with absence deformity of leg-autosomal recessive 33. Cataract, congenital, with microcornea or slight microphthalmia-X-linked 34. Cataract, cortical, and congenital ichthyosis-autosomal recessive 35. Cataract, mental retardation, hypogonadism (Martsolf syndrome) 36. Cataract, microcephaly, arthrogryposis kyphosis syndrome (CAMAK syndrome)-autosomal recessive 37. Cataract microcephaly, failure to thrive, kyphoscoliosis syndrome (CAMFAK syndrome)-autosomal recessive 38. Cataract, nuclear and total nuclear-usually autosomal dominant rarely recessive 39. Cataract, zonular, and nystagmus-X-linked 40. Cat-eye syndrome (Schmid-Fraccaro syndrome) 41. Cerebral cholesterinosis (cerebrotendinous xanthomatosis) 42. Cerebellar ataxia, cataract, deafness, and dementia or psychosis 43. Cerebral palsy 44. Cerebrohepatorenal syndrome (Smith-Lemli-Opitz syndrome) 45. Cerebrotendinous xanthomatosis 46. Cholera 47. Chromosome 13q partial deletion (long-arm) syndrome 48. Chromosomal 3; 18 translocation 49. Chromosome deletion (short-arm) syndrome 50. Cockayne syndrome (dwarfism with retinal atrophy and deafness) 51. Cerebrooculofascioskeletal syndrome (COFS syndrome) 51A Cohen syndrome, 52. Congenital cataract and hypertrophic cardiomyopathy syndrome 53. Congenital cataract with oxycephaly (tower skull) 54. Congenital hemolytic icterus 55. Congenital ichthyosiform erythroderma 56. Congenital rubella syndrome (German measles) 57. Conradi syndrome (stippled epiphyses syndrome) 58. Comedo-cataract 59. Craniofacial dysostosis (Crouzon disease) 60. Cretinism (hypothyroidism) 61. Crome syndrome (congenital cataracts, epileptic fits, mental retardation, small stature) 62. Cushing syndrome 63. Cytomegalovirus 64. Darier-White syndrome (keratosis follicularis) 65. DeBarsy syndrome 65A Degos disease,  66. Dermatitis herpetiformis *67. Diabetes mellitus (Willis disease) Type I and Type 2 68. Diarrhea 69. Diphtheria 69A Dubowitz syndrome 70. Ectodermal dysplasia 71. Edward syndrome 72. Electrical injury 73. Ellis-van Creveld syndrome (chondroectodermal dysplasia) 74. Engelmann syndrome (diaphyseal dysplasia) 75. Epidermal nevus syndrome (ichthyosis hystrix) 76. Fabry disease (diffuse angiokeratosis) 77. Familial congenital cataracts, microcornea, abnormal irides, nystagmus, and glaucoma syndrome 78. Familial congenital cataract, nonprogressive neurologic disorders, and mental deficiency syndrome 79. Familial histiocytic dermatoarthritis syndrome 80. Familial hypogonadism syndrome 81. Familial t(2;16) translocation 82. Fetal alcohol syndrome 83. Folling syndrome (phenylketonuria) 84. François dyscephalic syndrome (Hallermann-Streiff syndrome) 85. Frenkel syndrome (ocular contusion syndrome) 86. Fuchs syndrome (I) (heterochromic cyclitis syndrome) 87. Galactokinase deficiency-autosomal recessive *88. Galactosemia-transferase deficiency 88A GENETIC PREDISPOSITION of any kind 89. Goldenhar syndrome (oculoauriculovertebral dysplasia) 90. Goldscheider syndrome (epidermolysis bullosa) 91. Gorlin-Goltz syndrome (multiple basal cell nevi syndrome) 92. Grönblad-Strandberg syndrome (pseudoxanthoma elasticum) 93. Gyrate atrophy (ornithine ketoacid aminotransferase deficiency) 94. Hagberg-Santavuori syndrome (neuronal ceroid-lipofuscinosis) 95. Hallermann-Streiff syndrome (oculomandibulofacial dyscephaly) 96. Hand-Schüller-Christian syndrome (histiocytosis X) 97. Harada disease (uveitis-vitiligo-alopecia-poliosis syndrome) 98. Heerfordt syndrome (uveoparotid fever) 99. Hemifacial microsomia syndrome (François- Haustrate syndrome) 100. Herpes simplex virus 101. Hilding syndrome (destructive iridocyclitis and multiple joint dislocations) 102. Hodgkin disease 103. Homocystinuria 104. Hookworm disease 105. Hruby-Irvine-Gass syndrome (cystoid maculopathy following cataract extraction with vitreous loss) 106. Hutchinson-Gilford syndrome (progeria) 107. Hydatid cyst 108. Hypercalcemia (adult) 109. Hypercalcemia (infantile) with mental retardation (supravalvular aortic stenosis syndrome) 110. Hyperprolactinemia 111. Hypertrophic cardiomyopathy 112. Hypervitaminosis A 113. Hypervitaminosis D 114. Hypocalcemia 115. Hypoglycemia 116. Hypoparathyroidism 117. Hypophosphatasia (phosphoethanolaminuria) 118. Incontinentia pigmenti achromians 119. Infantile hypoglycemia (male) 120. Influenza 121. Infrared radiation 122. Intrauterine infections  A. herpes virus  B. mumps  C. rubella  D. toxoplasmosis  E. vaccinia 123. Jacobsen-Brodwall syndrome 124. Jadassohn-Lewandowsky syndrome (pachyonychia congenita) 125. Karsch-Neugebauer syndrome (nystagmus-split hand syndrome) 126. Klippel-Trenaunay-Weber syndrome (angioosteohypertrophy syndrome) 127. Krause syndrome (congenital encephaloophthalmic dysplasia) 128. Kussmaul disease (periarteritis nodosa) 129. Kyrle disease (hyperkeratosis penetrans) 130. Lanzieri syndrome (craniofacial malformations) 131. Laser treatment for retinopathy of prematurity 132. Laurence-Moon-Biedl syndrome (retinitis pigmentosa-polydactyly-adiposogenital) 133. Leber syndrome (optic atrophy-amaurosis-pituitary syndrome) 134. Leiomyoma 135. Leri syndrome (carpal tunnel syndrome) 136. Lightning 137. Listerellosis *138. Lowe syndrome (oculocerebrorenal syndrome) 139. Majewski syndrome (short-rib polydactyly syndrome) 140. Malaria 141. Male Turner syndrome (Noonan syndrome) 142. Malignant hyperpyrexia syndrome 143. Mandibulofacial dysostosis (Franceschetti syndrome) 144. Mannosidosis 145. Maple-syrup urine disease (branched-chain ketoaciduria 146. Marfan syndrome (arachnodactyly dystrophia mesodermaliscongenita) 147. Marinesco-Sjögren syndrome (congenital cataract-oligophrenia syndrome) 148. Marshall syndrome (atypical ectodermal dysplasia) 149. Martsolf syndrome 150. Matsoukas syndrome (oculocerebroarticuloskeletal syndrome) 151. Meckel syndrome (dysencephalia splanchnocystic syndrome) 152. Microcephaly, microphthalmia, cataracts, and joint contractures syndrome 153. Microphthalmia-congenital anterior polar cataract syndrome-autosomal dominant 154. Micro syndrome 155. Miller syndrome (Wilms aniridia syndrome) 156. Monilethrix 157. Morgan syndrome (intracranial exostosis) 158. Morquio-Brailsford syndrome (mucopolysaccharidoses IV) 159. Multiple sulfatase deficiency 160. Myopic (high) 161. Myotonic dystrophy (Curschmann-Steinert syndrome) 162. Nail-patella syndrome (Little syndrome) 163. Nance-Horan syndrome (cataract-dental syndrome) 164. Neurodermatitis 165. Neurofibromatosis 1 (von Recklinghausen syndrome) 166. Neurofibromatosis 2 (central neurofibromatosis) 167. Nieden syndrome (telangiectasia-cataract syndrome) 168. Norrie disease 169. Oculootoororenoerythropoietic disease 170. Optic atrophy, cataract, and neurologic disorder-autosomal dominant 171. Osteogenesis imperfecta congenita, microcephaly, and cataracts-autosomal recessive 172. Osteopetrosis (Albers-Schönberg syndrome) 173. Oxycephaly 174. Pachyonychia congenita syndrome 175. Paget syndrome (idiopathic hyperphosphatasemia) 176. Pallister-Killian syndrome 177. Partial trisomy 10q trisomy 178. Passow syndrome (syringomyelia) 179. Patau syndrome 180. Pellagra (avitaminosis B2) 181. Pemphigus foliaceus (Cazenave disease) 182. Pernicious anemia syndrome (vitamin B12 deficiency) 183. Pierre Robin syndrome (micrognathia-glossoptosis syndrome) 184. Prader-Labhart-Willi syndrome (hypogenital dystrophy with diabetic tendency) 185. Pseudoexfoliation syndrome 186. Pseudohypoparathyroidism 187. Radiation 188. Reese-Ellsworth syndrome (anterior chamber cleavage syndrome) 189. Refsum syndrome (phytanic acid storage disease) 190. Renal failure (chronic) 191. Renal transplantation 192. Retinal ischemic infarction syndrome *193. Retinitis pigmentosa-deafness-ataxia syndrome 194. Rhizomelic chondrodysplasia punctata 195. Riboflavin deficiency syndrome (oculoorogenital syndrome) 196. Ring chromosome in the D group 197. Robert syndrome 198. Robert pseudothalidomide syndrome 199. Romberg syndrome (facial hemiatrophy) 200. Rothmund syndrome (infantile poikiloderma) *201. Roy syndrome I (unilateral cataract associated with smoking) 202. Roy syndrome II-nuclear cataract associated with smoking 203. Rubeola (measles) 204. Rubinstein-Taybi syndrome (broad-thumbs syndrome) 205. Scaphocephaly syndrome (craniofacial dysostoses) 206. Schaefer syndrome (congenital dyskeratosis) 207. Schwartz syndrome 208. Scurvy (avitaminosis C) 209. Sickle cell disease (Herrick syndrome) 210. Siemen syndrome (congenital atrophy of the skin) 211. Sjögren syndrome (secretoinhibitor syndrome) 212. Sjögren-Larsson syndrome (oligophrenia ichthyosis) 213. Smith-Lemli-Opitz syndrome 214. Split-hand with congenital nystagmus, fundal changes, cataracts-autosomal dominant 215. Spondyloepiphyseal dysplasia (SED) dwarfism 216. Stannus cerebellar syndrome (vitamin B2 deficiency) 217. Stickler syndrome (hereditary progressive arthro-ophthalmopathy) *218. Still disease (juvenile rheumatoid arthritis) 219. Thrombocytopenia-absent radius (TAR) syndrome 220. Toxocariasis (nematode ophthalmia syndrome) 221. Treacher Collins syndrome (mandibulofacial dysostosis) 221A TRAUMA of any kind 222. Trichomegaly, spherocytosis, and cataract -autosomal dominant 223. Trichorrhexis nodosa (argininosuccinicaciduria) 224. Trisomy 13 syndrome (Patau syndrome) 225. Trisomy 16 syndrome (Edward syndrome) 226. Trisomy 20p syndrome 227. Trisomy 21 (Down syndrome) 228. Tuomaala-Haapanen syndrome 229. Turner syndrome (gonadal dysgenesis) 230. Tyrosinosis (Hanhart syndrome) 231. Usher syndrome (hereditary retinitis pigmentosa-deafness syndrome) 232. Uvea-touch syndrome 233. Van der Hoeve syndrome (brittle-bone disease) 234. Van Bogaert-Scherer-Epstein syndrome (primary hyperlipidemia) 235. Varicella infection 236. von Recklinghausen syndrome (neurofibromatosis) 237. Wagner syndrome (hyaloideoretinal degeneration) 283. Warburg syndrome (hydrocephalus, agyria, and absent cortical laminar retinal dysplasia with or without encephalocele) 239. Ward syndrome (nevus-jaw cyst syndrome) 240. Wegener syndrome (Wegener granulomatosis) 241. Weil disease (leptospirosis) 242. Werner syndrome (scleropoililoderma) 243. Wilson disease (hepatolenticular degeneration) 244. Yersiniosis 245. Zellweger syndrome (cerebrohepatorenal syndrome) 246. 31 syndrome 247. 4p syndrome 248. l8p syndrome 249. l8q syndrome Christiansen JP. Bradford JD. Cataract in infants treatment with argon laser photocoagulation for threshold retinopathy of prematurity. Am J Ophthalmol 1995; 119:175-180. Francis PJ. et al. Visual outcome in patients with isolated autosomal dominant congenital cataract. Ophthalmology 2001; 108:1104-1108. Ng JS. et al. Ocular complications of pediatric bone marrow transplantation. Ophthalmology 1999; 106:160-164. Pau H. Differential diagnosis of eye diseases. 2nd ed. New York: Thieme Medical, 1988. Roy FH. Ocular syndromes and systemic diseases. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2002.